<正> The authors made rat model of chronic renal failure by feeding the animals with foodcontaining 0.5 % adenine and treated with Niaoduqing（NDQ）

a Chinese patent medicine

whichcomposed of Rhizoma Rhei

Radix Glycyrrhizae

Radix Paeoniae Alba

etc.The rats were divid-ed into four groups:model control

normal control;and two NDQ-treated groups with high andlow doses separately.The blood tests including urea nitrogen（BUN）

serum creatinine（Scr）

red blood cell（RBC）

hemoglobin （Hb） hematocrit （HCT）

sodium （Na）

potassium （K）

cal-cium（Ca）and phosphate（P）levels were performed atthe fourth week and the eighth week

thetime of sacrifice.The results showed that in the NDQ-treated groups the mean levels of BUN andScr were lower and the mean values of RBC

Hb and HCT

higher than those in the untreatedcontrol group.In the NDQ-treated groups

hyperphosphatemia and hypocalcemia of rats im-proved

the deposited crystals of adenine metabolite and the proliferation of fibroid tissue in kid-ney decreased.These findings indicate that NDQ can ameliorate the symptoms of chronic renalfailure and delay the progress of this disease.