Relationship of hepatitis C virus infection with primary hepatic carcinoma: an investigation of serum HCV RNA in different population groups
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Relationship of hepatitis C virus infection with primary hepatic carcinoma: an investigation of serum HCV RNA in different population groups
Military Medical ResearchIssue 2, Pages: 109-113(1993)
Affiliations:
1. Department of Gastroenterology Southwest Hospital
2. Third Military Medical College
3. ,Chongqing,630038
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Published:1993
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[1]杨建民,刘为纹,晋华源.Relationship of hepatitis C virus infection with primary hepatic carcinoma: an investigation of serum HCV RNA in different population groups[J].Journal of Medical Colleges of PLA,1993(02):109-113.
DOI:
[1]杨建民,刘为纹,晋华源.Relationship of hepatitis C virus infection with primary hepatic carcinoma: an investigation of serum HCV RNA in different population groups[J].Journal of Medical Colleges of PLA,1993(02):109-113.DOI:
Relationship of hepatitis C virus infection with primary hepatic carcinoma: an investigation of serum HCV RNA in different population groups
摘要
Abstract
<正> A preliminary study on the serum hepatitis C virus(HCV)RNA in 182 pa-tients with different chronic liver diseases and 35 blood donors was carried out with“nested”polymerase chain reaction.It was found that serum HCV RNA was detected in36.6%(34/93)cases of primary hepatic carcinoma(PHC)
31.7%(20/63)liver cirrhosis
15.4%(4/26)chronic hepatitis and 2.9%(1/35)blood donors;most of the HCV RNA pos-itive cases(41/58)were complicated with HBV replicating markers;the rate of single posi-tive for HCV RNA was 15.1%(14/93)in PHC
3.2%(2/63)in liver cirrhosis
and 3.8%(1/26)in chronic hepatitis.These findings imply that about 20% of PHC cases appear tobe related to the coinfection of HCV and HBV and 15% of PHC cases are related to sin-gle HCV infection.
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