Immunohistochemical detection of ras p21 expression in pancreatic adenocarcinoma and its clinicopathological significance

胡育新; 许国铭

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Immunohistochemical detection of ras p21 expression in pancreatic adenocarcinoma and its clinicopathological significance

Updated：2026-03-12

- Immunohistochemical detection of ras p21 expression in pancreatic adenocarcinoma and its clinicopathological significance
- Military Medical Research Issue 4, Pages: 360-362(1993)
- Affiliations：
  
  1. Department of Gastroenterology Changhai Hospital
  2. Second Military Medical University
  3. ,Shanghai,200433
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：1993
- Accepted：
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[1]胡育新,许国铭.Immunohistochemical detection of ras p21 expression in pancreatic adenocarcinoma and its clinicopathological significance[J].Journal of Medical Colleges of PLA,1993(04):360-362.
DOI：

[1]胡育新,许国铭.Immunohistochemical detection of ras p21 expression in pancreatic adenocarcinoma and its clinicopathological significance[J].Journal of Medical Colleges of PLA,1993(04):360-362. DOI：

摘要

Abstract

<正> By using anti-ras p21 mouse monoclonal antibody（McAb）

SCI-oncogema 1

the au-thors examined immunohistochemical staining in pancreatic adenocarcinoma.The percentage ofpositive staining was 55.8%（24/43）and was related to either histopathological grade or clinicalstage.Upon statistical analysis of the correlation between the positive staining of anti-ras p21and patient prognosis with Klaplan-Meier curve and Log-rant test

the positive staining casesshowed comparatively better prognosis than the negative ones

suggesting that ras p21 expres-sion may be important in the early stage of pancreatic carcinoma.

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