Effect of vasoactive intestinal peptide on proliferation of hepatoma cells

黄晓峰; 张远强; 补永安; 苏慧慈

Your Location：

Home >

Browse articles >

Effect of vasoactive intestinal peptide on proliferation of hepatoma cells

Updated：2026-03-12

- Effect of vasoactive intestinal peptide on proliferation of hepatoma cells
- Military Medical Research Issue 3, Pages: 254-258(1993)
- Affiliations：
  
  1. Department of Histology and Embrology Fourth Military Medical University
  2. ,Xi’an,710032
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：1993
- Accepted：
Scan QR Code
[1]黄晓峰,张远强,补永安,苏慧慈.Effect of vasoactive intestinal peptide on proliferation of hepatoma cells[J].Journal of Medical Colleges of PLA,1993(03):254-258.
DOI：

[1]黄晓峰,张远强,补永安,苏慧慈.Effect of vasoactive intestinal peptide on proliferation of hepatoma cells[J].Journal of Medical Colleges of PLA,1993(03):254-258. DOI：

摘要

Abstract

<正> It has been found that vasoactive intestinal peptide （VIP） stimulates the growth ofseveral kinds of tumor cells.There is no report so far about the effect of VIP on the growth ofhepatoma cells.Using the tetrazolium colorimetric assay （MTT assay） and cell countingmethod

it was investigated that the effect of VIP on the growth of a cultured rat hepatomaFSK-7902 cells.The results showed that VIP stimulated the proliferation of the rat hepatomacells obviously.The addition of 1μmol/L VIP caused a significant increase in the number of thecultured rat hepatoma cells on 3rd day and maximal increase occured on 4th day and 5th day （ P<0.01）.The growth promoting effect was greater as the concentration of VIP increased.Thelowest effective concentration of VIP was 0.5μmol/L.Exposure to VIP for 12 h followed by re-moval of the peptide resulted in sustained growth for several days.

关键词

Keywords

references

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

⁰