Studies on the oxidative modification of low density lipoprotein induced by ultraviolet light and the protective effect of green tea polyphenols

丁振华; 陈瑷; 周玫; 方允中

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Studies on the oxidative modification of low density lipoprotein induced by ultraviolet light and the protective effect of green tea polyphenols

Updated：2026-03-12

- Studies on the oxidative modification of low density lipoprotein induced by ultraviolet light and the protective effect of green tea polyphenols
- Military Medical Research Issue 2, Pages: 121-126(1992)
- Affiliations：
  
  1. Research Group of Lipoperoxidation Damage First Military Medical University
  2. ,Guangzhou,510515
  3. Department of Biochemistry
  4. Institute of Radiation Medicine
  5. Academy of Military Medical Sciences.,Beijing,100850
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：1992
- Accepted：
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[1]丁振华,陈瑷,周玫,方允中.Studies on the oxidative modification of low density lipoprotein induced by ultraviolet light and the protective effect of green tea polyphenols[J].Journal of Medical Colleges of PLA,1992(02):121-126.
DOI：

[1]丁振华,陈瑷,周玫,方允中.Studies on the oxidative modification of low density lipoprotein induced by ultraviolet light and the protective effect of green tea polyphenols[J].Journal of Medical Colleges of PLA,1992(02):121-126. DOI：

摘要

Abstract

正

Uitraviolet（UV）light irradiation acting on human low density lipoprotein（LDL）couldgive rise to oxidative modification of LDL.Thiobarbituric acid reactive substances（TBARS）

rela-five electrophorefic mobility（REM）

relative fluorescence intensity at 420 nm（the excitation wavelength was 360nm）and lipid conjugated dienes of UV-irradiated LDL were all elevated withthe increase of irradiation time.Addition of 0.01％ EDTA into the irradiation system could inhi-bit this reaction

but the effect was not so potent as that induced in the Cu

-PBS-LDLoxidative modification system China green tea polyphenols（CGTP）

on the other hand

had aneffective inhibitory effect with obvious dose-effect relationship.It was proposed that lipidperoxidation of LDL induced by free radicals which were generated from UV-irradiation andthe inhibitory effect of CGTP was attributed to its strong antioxidative action.

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