<正> In the present investigation

measurement of leukocyte chemiluminescence （CL） wasundertaken using micro-whole blood assay in 76 patients with coronary heart diseases （CHDs）.The findings showed that there was a significant increase in leukocyte CL in patients with un-stable angina pectoris （UAP） and acute myocardial infarction （AM1） （P<0.01） and the in-crease was greater in AMI than that in UAP （P<0

01）.It was found that leukocyte CL inAMI was correlated with the extent of the infarct and increased with the size of the infarct.Leukocyte CL in AMI patients who had received fibrinolytic treatment was markedly greaterthan that before treatment （P<0.05）

suggesting that leukocytes may play an important rolein the pathogenesis of CHDs and may be involved in myocardial ischemia-reperfusion induced in-jury.The findings of the present study demonstrate that measurement of leukocyte CL may beof benefits for prognosis and treatment of CHDs.