<正>Objective: To observe the central nervous system （CNS） complications among 1083 consecutive renal transplant （RT） recipients. Methods: Systemic analyses of the incidence

time of onset and clinical outcome of CNS complications were conducted in 1083 patients receiving cadaveric RT in Nanfang Hospital during Jan 1992 to Dec 1999. Results: Various CNS complications occurred in a total of 68 RT recipients （6. 28%

68/1083） with a mortality of （1. 29%

14/1083）. Of all the 1 083 recipients enrolled in this study

diffuse encephalopathy occurred in 31 cases （2. 86%）

cerebrovascular accidents in 17 （1. 56%）

seizure in 11 （1. 02%） and CNS infection in 9 （0. 83%）. Immusuppressive agents was the major cause for diffuse encephalopathy （93. 5%

29/31）

and cerebrovascular accidents were associated with a mortality rate of 70. 5% （12/17） and CNS infection with a mortality rate of 22. 22% （2/9）. Most of the complications took place within the first month after RT

especially the first 2 weeks

but the majority of