Microarray analysis of genes differentally expressed in placentas of pregnancy-induced hypertension patients

李东红; 黄飞; 郑维国; 姜锋; 高平

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Microarray analysis of genes differentally expressed in placentas of pregnancy-induced hypertension patients

Updated：2026-03-12

- Microarray analysis of genes differentally expressed in placentas of pregnancy-induced hypertension patients
- Military Medical Research Issue 2, Pages: 105-108(2003)
- Affiliations：
  
  1. Department of Obstetrics & Gynecology
  2. Tangdu Hospital
  3. Fourth Military Medical University
  4. ,Xi’an,710033
  5. Xijing Hospital
- Author bio：
- Funds：
- DOI：
  CLC： R714.246
- Published：2003
- Accepted：
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[1]李东红,黄飞,郑维国,姜锋,高平.Microarray analysis of genes differentally expressed in placentas of pregnancy-induced hypertension patients[J].Journal of Medical Colleges of PLA,2003(02):105-108.
DOI：

[1]李东红,黄飞,郑维国,姜锋,高平.Microarray analysis of genes differentally expressed in placentas of pregnancy-induced hypertension patients[J].Journal of Medical Colleges of PLA,2003(02):105-108. DOI：

摘要

Abstract

<正> Objective: To uncover new clue for the research of the etiology of pregnancy-induced hypertension （PIH）by testing the gene expression difference between preeclamptic placentas and normal ones. Methods: mRNA level of 4PIH placentas were examined using 4000 feature cDNA microarray in comparison with the pooled control consisting oftotal RNA from 4 cases of PIH placentas after the control cDNA and experimental cDNA were labeled by cy3 and cy5respectively. Results: Fifty-eight to 131 genes were found down or up-regulated in 4 runs of hybridization. Among the

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