Expression of PKD2 gene in human renal tissue and other tissues

周玉坤; 沈学飞; 梅长林; 汤兵; 孙田美; 宋吉

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Expression of PKD2 gene in human renal tissue and other tissues

Updated：2026-03-12

- Expression of PKD2 gene in human renal tissue and other tissues
- Military Medical Research Issue 5, Pages: 293-296(2004)
- Affiliations：
  
  1. Department of Nephrology Changzheng Hospital
  2. Second Military Medical University
  3. Kidney Disease Center of PLA
  4. ,China
- Author bio：
- Funds：
- DOI：
  CLC： R346
- Published：2004
- Accepted：
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[1]周玉坤,沈学飞,梅长林,汤兵,孙田美,宋吉.Expression of PKD2 gene in human renal tissue and other tissues[J].Journal of Medical Colleges of PLA,2004(05):293-296.
DOI：

[1]周玉坤,沈学飞,梅长林,汤兵,孙田美,宋吉.Expression of PKD2 gene in human renal tissue and other tissues[J].Journal of Medical Colleges of PLA,2004(05):293-296. DOI：

摘要

Abstract

<正>Objective: To study the expression of PKD2 gene in human kidney and other tissues. Methods: The expression of PKD2 was detected by reverse transcription PCR（RT-PCR） and in situ hybridization（ISH） . The results of ISH were analyzed by micromegakargooytes. Results: Distribution of pkd-2 in normal adult kidney was stronger in proximal convoluted tubule

Henle’s loop ascending branch

distal convoluted tubule and cortical collecting ducts

and inferior signal were observed in fetal kidney. Negative was seen in ADPKD 2 kidney. Conclusion: Down-regulation of PKD2 gene expression in kidney may take effect on the occurrence and development of ADPKD2.

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