Altofrequency SNPs of mitochondrial DNA in 26 Han Chinese
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Altofrequency SNPs of mitochondrial DNA in 26 Han Chinese
Military Medical ResearchIssue 2, Pages: 67-71(2007)
Affiliations:
1. Department of Pathophysiology and High Altitude Physiology College of High Altitude Military Medicine Third Military Medical University
2. Department of Immunology College of Basic Medicine
3. Center for Disease Control and Prevention PLA Chengdu Military Area Command
4. ,Chengdu,610021
Author bio:
Funds:
DOI:
CLC:R394
Published:2007
Accepted:
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[1]罗勇军,高文祥,高钰琪,陈建,谭小玲,刘昕,陈海华.Altofrequency SNPs of mitochondrial DNA in 26 Han Chinese[J].Journal of Medical Colleges of PLA,2007(02):67-71.
DOI:
[1]罗勇军,高文祥,高钰琪,陈建,谭小玲,刘昕,陈海华.Altofrequency SNPs of mitochondrial DNA in 26 Han Chinese[J].Journal of Medical Colleges of PLA,2007(02):67-71.DOI:
Altofrequency SNPs of mitochondrial DNA in 26 Han Chinese
摘要
Abstract
<正>Objective: To explore the possible mitochondrial DNA (mtDNA) polymorphism in Han Chinese. Methods: The complete mitochondrial genome of 26 unrelated healthy Han Chinese were extracted and sequenced. Results:The mtDNA nucleotide sites (2 706
7 028
8 860
11 719
and 15 326) were found totally different from the Revised Cambridge Reference Sequence (rCRS). These single nucleotide polymorphisms (SNPs) were 2 706 A→G
7 028 C→T
8 860 A→G
11 719 G→A
15 326 A→G. Conclusion: These findings provide new insights into the characteristics of Han Chinese mitochondrial genetic diversity.
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