<正>Airway management in the patients who receive transmaxillary approach for resection of giant pituitary tumor presents a clinical challenge to the anesthesiologists.Oral or nasal route for tracheal intubation can interfere with surgical procedures.This report describes submental tracheal intubation for airway management in a patient who underwent resection of recurrent giant pituitary tumor via transmaxillary approach.Submental tracheal intubation is an adaptable and safe alternative technology for airway management during operation.