HBsAg seroprevalence among Senegalese militaries

Abdoul Aziz Ndiaye; Ibrahima Socé Fall; Gora Lo; Sidy Mouhamed Seck; Alioune Badara Tall; Boubacar Gueye; Amady Barro Mbodj; Anta Tal-Dia

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HBsAg seroprevalence among Senegalese militaries

RESEARCH | Updated：2022-12-27

- HBsAg seroprevalence among Senegalese militaries
- Military Medical Research Vol. 1, Issue 4, Pages: 203-207(2014)
- Affiliations：
  
  1.Community Health Department, University Alioune Diop of Bambey, Bambey City, Senegal
  2.Army Health Service, Camp Dial Diop Dakar, Senegal
  3.Faculty of Health Sciences, Gaston Berger University, Saint-Louis, Senegal
  4.Public Health Department, Cheikh Anta Diop University, Dakar, Senegal
  5.WHO Mali
- Author bio：
  
  *: socef@who.int (IS Fall),
- Funds：
- DOI：
  CLC：
- Published：2014-12
- Accepted：
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Ndiaye et al.: HBsAg seroprevalence among Senegalese militaries. Mil Med Res 2014
DOI：

Ndiaye et al.: HBsAg seroprevalence among Senegalese militaries. Mil Med Res 2014 DOI：

摘要

Abstract

Background:

Chronic hepatitis is a major public health problem. The hepatitis B virus is the primary cause

and Hepatitis B and C together are responsible for 60% of cirrhosis and 80% of hepatocellular carcinomas. This study measured the prevalence of HBsAg among Senegalese military to develop a strategy to prevent cirrhosis and hepatocellular carcinoma in the army.

Methods:

We conducted a descriptive cross-sectional study among Senegalese army staff aged 25 to 60 years and divided this group into three strata: 25-34

35-44 and 45-60 years. A sample of 1224 participants was selected following a two-level stratification. The mark of surface HBs antigen (Ag) was performed on 1195 participants using chemiluminescence (qualitative Architect HBs Ag of Abbott Diagnostics Laboratories Germany) and enzyme immunoassay (Determines HBsAg) methods. The presence of HBsAg was analyzed according to age

marital status

alcohol consumption and glomerular filtration rate. Epi-info6 and R software were used

respectively

for data capture and analyses. A Chi-square test was performed to compare proportions considering an alpha significance level of 5% and a confidence interval of 95%.

Results:

The average age was 39.8±9.2 years. Participants in the age groups of 25-34 years

45-60 years and 35-44 years were 30.7%

34.4% and 34.9% of the sample

respectively. Married persons accounted for 82.6% of participants

and 17.08% were single. Most participants were educated (99%)

and 56% had reached at least the secondary school level. Alcohol consumption was at 11.5%. The HBsAg prevalence rate was 10.8% [9.1% to 12.7%] with a significant difference between age groups (P<0.001)

which ranged from 5.6% for 45-60 years

9.62% in the 25-34 years group and 16.9% for the 35-44 years group. Marital status and alcohol consumption did not affect the carriage of HBsAg. The prevalence of HBsAg was more common among participants who had a glomerular filtration rate greater than 90 ml/min. Transaminases rate exceeded the normal threshold in 43 participants (3.6%). The increase was 6.6% [2.7% to 11.8%] of HBsAg carriers and 3.2% [1.2% to 6.7%] of alcohol users.

Conclusion:

The high prevalence of HBsAg in the military requires the implementation of an accessible prevention and care program to reduce the risk of cirrhosis and hepatocellular carcinoma. This program will contribute to reducing the burden of communicable diseases

such as hepatitis and HIV/AIDS

and non-communicable diseases in the armed forces.

关键词

Keywords

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