Coagulation complications following trauma

Wenjun Z. Martini

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Coagulation complications following trauma

REVIEW | Updated：2022-12-27

- Coagulation complications following trauma
- Military Medical Research Vol. 4, Issue 2, Pages: 93-100(2017)
- Affiliations：
  
  U.S. Army Institute of Surgical Research, 3698 Chambers Pass, JBSA-Fort Sam Houston, Houston, TX 78234-6315, USA
- Author bio：
  
  wenjun.z.martini.civ@mail.mil
- Funds：
- DOI：
  CLC：
- Published：2017-06
- Accepted：
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Wenjun Z. Martini. Coagulation complications following trauma[J]. Military Medical Research, 2017, 4(2): 93-100.
DOI：

Wenjun Z. Martini. Coagulation complications following trauma[J]. Military Medical Research, 2017, 4(2): 93-100. DOI：

摘要

Abstract

Traumatic injury is one of the leading causes of death

with uncontrolled hemorrhage from coagulation dysfunction as one of the main potentially preventable causes of the mortality. Hypothermia

acidosis

and resuscitative hemodilution have been considered as the significant contributors to coagulation manifestations following trauma

known as the lethal triad. Over the past decade

clinical observations showed that coagulopathy may be present as early as hospital admission in some severely injured trauma patients. The hemostatic dysfunction is associated with higher blood transfusion requirements

longer hospital stay

and higher mortality. The recognition of this early coagulopathy has initiated tremendous interest and effort in the trauma community to expand our understanding of the underlying pathophysiology and improve clinical treatments. This review discusses the current knowledge of coagulation complications following trauma.

关键词

Keywords

references

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